Polysialic Acid in Molecular Medicine

The colominic acid was covalently coupled to L asparaginase molecule by reductive amination.

最近 ,Ｇｒｅｇｏｒｉａｄｉｓ等人[2 ] 认为可以使用多聚唾液酸代替ｍＰＥＧ分子来修饰药物。

The endoneuraminidase NE (endo-N) which specifically removes a-2, 8 linked polysialic acidfrom NCAM was used to assay the functional role of PSA in the chicks memory retention.

神经细胞粘附分子的多聚唾液酸化不仅影响发育阶段神经元之间的相互作用，而且在学习记忆过程中也起着重要的作用。

Objective To study the effect of behavior training on the expression of polysialic acid-neural cell adhesion molecule ( PSA-NCAM) around the focus of an infarction in the left hippocampal dentate gyrus ( DG) in rats.

目的研究行为学训练对大鼠海马梗死后齿状回区多聚唾液酸神经细胞黏附分子(PSA- NCAM)表达及对神经干细胞迁移能力的影响。